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Welcome to the website of the
Southwest Virginia MS Support Group
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Tofranil (imipramine)


Description
Carbamazepine is used to relieve shock-like pain, such as the facial
pain caused by trigeminal neuralgia (tic douloureux).
Proper Usage
It is very important that you take this medicine exactly as directed
by your physician in order to obtain the best results and lessen the
chance of serious side effects.
Carbamazepine is not an ordinary pain reliever. It should be used only
when your physician prescribes it for certain types of pain. Do not take
this medication for other aches or pains.
If you miss a dose of this medication, take it as soon as possible. If
it is almost time for your next dose, skip the missed dose and go back to
your regular dosing schedule. Do not double dose. If you miss more than
one dose in a day, check with your physician.
It is very important that your physician check your progress at
regular intervals. Your physician may want to have certain tests done to
see if you are receiving the correct amount of medication or to check for
certain side effects of which you might be unaware.
Precautions
Carbamazepine adds to the effects of alcohol and other central nervous
system depressants that may cause drowsiness (e.g., antihistamines,
sedatives, tranquilizers, prescription pain medications, seizure
medications, muscle relaxants). Be sure that your physician knows if you
are taking these or other medications.
Some people who take carbamazepine may become more sensitive to
sunlight than they are normally. Exposure to sunlight, even for brief
periods of time, may cause a skin rash, itching, redness or other
discoloration of the skin, or severe sunburn.
Oral contraceptives (birth control pills) that contain estrogen may
not work properly while you are taking carbamazepine. You should use an
additional or alternative form of birth control while taking this drug.
Carbamazepine affects the urine sugar levels of diabetic patients. If
you notice a change in the results of your urine sugar tests, check with
your physician.
Before having any medical tests or any kind of surgical, dental, or
emergency treatment, be sure to let the health care professional know that
you are taking this medication.
Carbamazepine has not been studied in pregnant women. There have been
reports of babies having low birth weight, small head size, skull and
facial defects, underdeveloped fingernails, and delays in growth when
their mothers had taken carbamazepine in high doses during pregnancy.
Studies in animals have shown that carbamazepine causes birth defects when
given in large doses.
Carbamazepine passes into breast milk, and the baby may receive enough
of it to cause unwanted effects. In animal studies, carbamazepine has
affected the growth and appearance of nursing babies.
Possible Side Effects
Side effects that typically go away as your body adjusts to the
medication and do not require medical attention unless they continue for
several weeks or are bothersome: clumsiness or unsteadiness*; mild
dizziness*; mild drowsiness*; lightheadedness; mild nausea or vomiting;
aching joints or muscles; constipation*; diarrhea; dryness of mouth; skin
sensitivity to sunlight; irritation of mouth or tongue; loss or appetite;
loss of hair; muscle or abdominal cramps; sexual problems in males*.
Check with your physician as soon as possible if any of the following
side effects occur: blurred or double vision*; confusion; agitation;
severe diarrhea, nausea, or vomiting; skin rash or hives; unusual
drowsiness; chest pain; difficulty speaking or slurred speech*; fainting;
frequent urination*; unusual heartbeat; mental depression or other mood or
emotional changes; unusual numbness, tingling, pain, or weakness in hands
or feet*; ringing or buzzing in ears; sudden decrease in urination;
swelling of face, hands, feet, or lower legs; trembling; uncontrolled body
movements; visual hallucinations.
Check with your physician immediately if any of the following occur:
black tarry stools or blood in urine or stools; bone or joint pain; cough
or hoarseness; darkening of urine; nosebleeds or other unusual bleeding or
bruising; painful or difficult urination; tenderness, swelling, or bluish
color in leg or foot; pale stools; pinpoint red spots on skin; shortness
of breath or cough; sores, ulcers, or white spots on lips or in the mouth;
sore throat, chills, and fever; swollen glands; unusual tiredness or
weakness*; wheezing, tightness in chest; yellow eyes or skin.
Symptoms of overdose that require immediate attention: unusual
clumsiness or unsteadiness*; severe dizziness or fainting; fast or
irregular heartbeat; unusually high or low blood pressure; irregular or
shallow breathing; severe nausea or vomiting; trembling, twitching, and
abnormal body movements.
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Since it may be difficult to distinguish between certain common
symptoms of MS and some side effects of carbamazepine, be sure to
consult your health care professional if an abrupt change of this
type occurs.
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